Document Type : Research Paper
Authors
1 Ferdowsi University of Mashhad
2 Semnan University
Abstract
Vaccination and isolation are crucial strategies for controlling pandemics, but healthcare infrastructure constraints, such as limited medical resources and workforce shortages, often limit their effectiveness. This research explores the impact of these constraints on vaccination and isolation policies through the development of a Vaccination and Isolation Constraint-based Evolutionary Type-2 Fuzzy Controller (VIETFC) intended to assist policymakers. A genetic algorithm optimizes VIETFC's parameters to reduce the number of infected individuals and provide adequate medical care. As a realistic case study, we consider the COVID-19 pandemic and use a stochastic SEIAR (S2EIAR) model to include the pandemic's inherent uncertainties and establish four scenarios with progressively increasing constraints, with the fourth scenario reflecting the most realistic conditions. Results show that VIETFC adapts effectively to resource limitations, maintaining a 15% standard deviation despite a 50% parameter variation. VIETFC surpasses Proportional Integral Derivative (PID) and type-1 fuzzy controllers by offering interpretable solutions through a more practical resource allocation strategy. Future research should focus on enhancing the flexibility of this method for application to additional pandemic models.
Keywords
Main Subjects
algorithm to obtain the vaccination and isolation rates for the COVID-19, in 2021 29th Iranian Conference on
Electrical Engineering, ICEE 2021, IEEE, (2021), 731-735. https://doi.org/10.1109/ICEE52715.2021.9544298
Health, 25(1) (2025), 219. https://doi.org/10.1186/s12889-025-21401-7
19 outbreak, PLoS One, 15(3) (2020), e0230405. https://doi.org/10.1371/journal.pone.0230405
Proceedings of the IEEE Conference on Decision and Control, (2022), 5620-5626. https://doi.org/10.
1109/CDC51059.2022.9992682
estimation for the nonlinear epidemiological model of Covid-19, Nonlinear Dynamics, 109(1) (2022), 5-18. https:
//doi.org/10.1007/s11071-021-07036-4
optimal tuning of controllers for shape memory alloy wire actuators, IFAC-PapersOnLine, 55(15) (2022), 39-44.
https://doi.org/10.1016/j.ifacol.2022.07.605
present COVID-19 pandemic: Fractional-order chaotic models and fuzzy logic control, European Physical Journal:
Special Topics, 231(5) (2022), 905-919. https://doi.org/10.1140/epjs/s11734-021-00335-2
moment method-based reformulation, Computers in Biology and Medicine, 183 (2024), 109283. https://doi.org/
10.1016/j.compbiomed.2024.109283
Biophysical Research Communications, 555 (2021), 202-209. https://doi.org/10.1016/j.bbrc.2020.12.105
parameters for the spread of COVID-19, Mathematics and Computers in Simulation, 198 (2022), 31-46. https:
//doi.org/10.1016/j.matcom.2022.02.025
with vaccination, Mathematical Methods in the Applied Sciences, 48(3) (2025), 3936-3955. https://doi.org/10.
1002/mma.10526
of COVID-19 spread: A hybrid SEIRV-DNNs approach, Scientific Reports, 15(1) (2025), 2043. https://doi.org/
10.1038/s41598-025-85440-1
COVID-19 incorporating adverse events of the antiviral drugs, Computational and Mathematical Biophysics, 9(1)
(2021), 214-241. https://doi.org/10.1515/cmb-2020-0125
influenza: Mexico as a case study, PLoS One, 4(12) (2009), e8164. https://doi.org/10.1371/journal.pone.
0008164
in society, Research Square, (2021). https://doi.org/10.21203/rs.3.rs-941879/v1
controlling COVID-19, Scientific Reports, 11(1) (2021), 1-11. https://doi.org/10.1038/s41598-021-86873-0
SEIR model, Chaos, 30(11) (2020), 1-13. https://doi.org/10.1063/5.0015943
Signal Processing and Control, 64 (2021), 102317. https://doi.org/10.1016/j.bspc.2020.102317
of COVID-19 vaccine prioritization in the context of limited vaccination capacity, Nature Communications, 12(1)
(2021), 4673. https://doi.org/10.1038/s41467-021-24872-5
COVID-19 epidemic model with time-delay, Computers in Biology and Medicine, 141 (2022), 105115. https:
//doi.org/10.1016/j.compbiomed.2021.105115
COVID-19 in China, Nature, 582(7812) (2020), 389-394. https://doi.org/10.1038/s41586-020-2284-y
incorporating asymptomatic and super-spreader individuals, Mathematical Biosciences, 380 (2025), 109373. https:
//doi.org/10.1016/j.mbs.2024.109373
computational simulation reveals the importance of social distancing and mask usage, Computers in Biology and
Medicine, 134 (2021), 104369. https://doi.org/10.1016/j.compbiomed.2021.104369
administration in COVID-19 pandemic treatment, Computer Methods and Programs in Biomedicine, 196 (2020),
105664. https://doi.org/10.1016/j.cmpb.2020.105664
spread for pandemic forecasting based on Simulink, Physical Biology, 18(4) (2021), 1-20. https://doi.org/10.
1088/1478-3975/abf990
deterministic and stochastic SIDR models, Nonlinear Dynamics, 106(2) (2021), 1359-1373. https://doi.org/10.
1007/s11071-021-06680-0
uncertain SEIAR influenza epidemic model considering dynamic population, Journal of Theoretical Biology, 482
(2019), 109984. https://doi.org/10.1016/j.jtbi.2019.08.015
(2007), 20-29. https://doi.org/10.1109/MCI.2007.380672
rejection in autonomous vehicles with longitudinal movement, Iranian Journal of Fuzzy Systems, 22(1) (2025), 93-
110. https://doi.org/10.22111/ijfs.2025.48966.8628
dynamics in the Basque Country: Characterizing population immunity profile from 2020 to 2022, BMC Infectious
Diseases, 25(1) (2025), 9. https://doi.org/10.1186/s12879-024-10342-y
simulation of the COVID-19 pandemic with explicit behavioral changes in Bogot´a: A case study, Infectious Disease
Modelling, 7(1) (2022), 199-211. https://doi.org/10.1016/j.idm.2021.12.008
and Programs in Biomedicine, 211 (2021), 106411. https://doi.org/10.1016/j.cmpb.2021.106411
and control strategies, Journal of Applied Mathematics and Computing, 71(1) (2025), 573-604. https://doi.org/
10.1007/s12190-024-02238-6
optimization techniques applied to control and modeling, CRC Press, Taylor and Francis Group, (2025).
https://doi.org/10.1201/9781003488279
MedRxiv, (2020), 1-9. https://doi.org/10.1101/2020.04.19.20071654
on Fuzzy Systems, 31(7) (2022), 2251-2263. https://doi.org/10.1109/TFUZZ.2022.3222036
control, IEEE Transactions on Artificial Intelligence, 5(10) (2024), 4928-4937. https://doi.org/10.1109/TAI.
2024.3395416
modeling of COVID-19 spread based on vaccination and social distancing rates, Computer Methods and Programs
in Biomedicine, 232 (2023), 107443. https://doi.org/10.1016/j.cmpb.2023.107443
(2010), e1000793. https://doi.org/10.1371/journal.pcbi.1000793
Conference on Fuzzy Systems, Institute of Electrical and Electronics Engineers Inc., (2021). https://doi.org/10.
1109/FUZZ45933.2021.9494413
mode control with tower crane systems validation, Romanian Journal of Information Science and Technology, 27(1)
(2024), 50-64. https://doi.org/10.59277/ROMJIST.2024.1.04
Mathematics and Computers in Simulation, 200 (2022), 285-314. https://doi.org/10.1016/j.matcom.2022.04.
025
to mitigate the COVID-19 spread, IEEE Transactions on Automation Science and Engineering, 19(2) (2021),
560-575. https://doi.org/10.1109/TASE.2021.3111338
of contact transmission and environmental contamination, Gene, 941 (2025), 149033. https://doi.org/10.1016/
j.gene.2024.149033
classes in SiSAQEIHR model for pandemic control: A deep LSTM-RNN predictions, Physica D, 474 (2025),
134563. https://doi.org/10.1016/j.physd.2025.134563
2(4) (2014), 175-176. https://doi.org/10.1007/s13748-014-0051-8
and migrating: Case study of COVID-19 vaccination, Biomedical Signal Processing and Control, 71 (2022), 103227.
https://doi.org/10.1016/j.bspc.2021.103227
and Computers in Simulation, 185 (2021), 687-695. https://doi.org/10.1016/j.matcom.2021.01.022
of social isolation practices for COVID-19 outbreak response in residential care facilities, BMC Infectious Diseases,
24(1) (2024), 880. https://doi.org/10.1186/s12879-024-09788-x
and Computers in Simulation, 215 (2024), 498-517. https://doi.org/10.1016/j.matcom.2023.08.005